Removal of Certain Genes May Expanded Lifespan by 60 Percent
October, 18, 2015: For the last ten years, scientists have been attempting to identify the
genes that cause aging in humans. And after recent tests done on various strains of yeast, they found that there are 238 genes that, when
removed, significantly increase the lifespan of the yeast cells. In some circumstances, the lifespan of the cells was increased by as much as 60 percent.
Brian Kennedy, a lead author of the study and president and CEO of the Buck Institute of Research on Aging in the US, explained the yeast cell
study in his words, saying, “This study looks at aging in the context of
the whole genome and gives us a more complete picture of what aging is. It also sets up a framework to define the entire network that influences aging in this organism.”
The University of Washington helped the Buck Institute with the study and together they monitored the development of nearly 4,700 yeast cell
strains. Exactly one gene was deleted from each strain, after which the
time it took each strain to replicate was Unknown closely monitored. Scientists were reportedly looking specifically at how many
daughter cells the mother cells could produce by cell division.
We just need to determine which genes are capable of being safely altered or removed. One gene
called LOS1 that helps build proteins in our bodies seems to have a lot to do with it.
In the end, this long and tedious study of yeast cells produced results. Though some of the 238 genes identified were already known to be linked
with aging, 189 of them are new finds.