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Chemical Compounds in Mulhati
The chief constituent of Liquorice root is Glycyrrhizin (6 to 8 per cent), obtainable in the form of a sweet, white crystalline powder, consisting of the calcium and potassium salts of
glycyrrhizin acid. The
plant also contains sugar, starch (29 per cent), gum, protein, fat (0.8 per cent), resin, asparagin (2 to 4 per cent), a trace of tannin in the outer bark of the root, yellow colouring matter, and 0.03 of volatile oil.
Chemical Compounds: Triterpenes of the oleanane type, mainly glycyrrhizin
(glycyrrhizin acid), and its agylcone glycyrrhetinic acid, liquiritic acid, glycyrrhetol, glabrolide,
isoglabrolide, licoric acid, and phytosterols.
Flavonoids and isoflavonoids; liquiritigenin, liquiritin,
rhamnoliquiritin, neoliquiritin, licoflavonol, licoisoflavones A and B,
licoisoflavanone, formononetin, glabrol, glabrone, glyzarin, kumatakenin and others.
Coumarins; liqcoumarin, umbelliferone, herniarin glycyrin.
Chalcones; liquiritigenin, isoliquiritigenin, neosoliquiritin,
rhamnoisoliquiritin, licuraside, licochalcones A and B, echinatin and others.
Polysaccharides, mainly glucans.
Volatile oil, containing fenchone, linalool, furfuryl alcohol,
benzaldehyde.
Miscellaneous; starch, sugars, amino acid etc

Uses of Mulhati
Liquorice is largely used by brewers, being added to porter and stout to give thickness and blackness.
Block Liquorice is employed in the manufacture of tobacco for smoking and chewing.
In the United States a new use for Liquorice Root has
been discovered, the waste root being now utilized for the manufacture of boards for making boxes. After extraction of the
Liquorice, the crushed root was formerly considered a waste product and destroyed by burning, but under a recently discovered process this refuse can now be made into a chemical wood pulp and pressed into a board that is said to have satisfactory resisting qualities and strength.
The powdered root is useful in pill-making on account of its absorbent qualities, being used to impart stiffness to pill masses and to prevent the adhesion of pills.
Medicinal Properties
Liquorice is a popular and well-known remedy for coughs, consumption and chest complaints
generally, notably bronchitis, and is an ingredient in almost all popular cough medicines on account of its valuable soothing properties. The Extract enters into the composition of cough lozenges and pastilles, with sedatives and expectorants.
Fluid Extract of Liquorice is employed for disguising the taste of nauseous medicines, having a remarkable power of converting the flavour of acrid or bitter drugs.
Liquorice was prescribed by early physicians in cases of dropsy, to prevent thirst.
The sugar of Liquorice may safely be taken by diabetic patients.
It is used in a variety of medicinal preparations
possessing tonic, alterative and expectorant properties, and also for the rejuvenating and highly nutritive qualities attributed to it.
As an anti-hepatotoxic licorice is effective in the treatment of chronic hepatitis and cirrhosis, for which it is been widely used in Japan. Much of the liver orientated research has focused upon the triterpene glycyrrhizin. This inhibits hepatocyte injury caused by carbon tetrachloride, benzene hexachloride and PCB. Antibody production is enhanced by glycyrrhizin, possibly through the production of
interleukin.
Liquorice is used in allopathic medicine as a treatment for peptic ulceration, a similar use to its herbal use in
gastritis and ulcers. It can be used in the relief of abdominal colic. It nourishes the brain-increasing cranial and cerebrospinal fluid.
Liquorice also improves complexion, hair, and vision.
Some of the medicinal properties and uses of liquorice:
* Liquorice is a valuable remedy for relieving pain, discomfort and other symptoms caused by acrid matter in the stomach.
* Lubricating the throat with a decoction of liquorice mixed with honey brings relief in dry cough.
* It is an effective home remedy for sore throat. A small piece of raw liquorice if chewed or sucked provides relief by soothing the
inflammation.
* Liquorice is useful in treating pain due to stomach ulcers, as it soothes the irritation caused by acids. Pieces of the dried root soaked overnight in water and the infusion taken with rice gruel helps in the cure of ulcer.
* Liquorice alleviates muscular pains. Taking an infusion of the roots soaked overnight relieves any chronic joint problems.
* The powder of the herb mixed with butter or ghee and honey can be applied on cuts and wounds with good results. The leaves of the plant, applied as a poultice is a useful remedy in scalds of the head and body.
* It is used in the treatment of myopia. Half a teaspoon of the powder of the root, mixed with an equal amount of honey and half the quantity of ghee, can be given twice daily with milk on an empty stomach in this case.
* It heals corns which are just appearing. A paste of liquorice sticks mixed with sesame or mustard oil, if rubbed into the hardened skin at bed time softens the skin and the corn decreases in size.
* It is also used as a laxative in constipation. Its powder is taken with jaggery and water in this condition.
* The sticks of dried rhizomes are soaked in water and the infusion used as a gargle brings quick relief in oral inflammations. Tiny bits of the stick with sugar candy can also be sucked.
* Liquorice is beneficial in treating patchy baldness. Small pieces of the root are ground in milk with a pinch of saffron to a paste. When this paste is applied over the bald patches at bedtime regularly, hair growth is seen within a few weeks. This
is very effective in the initial stages of baldness, excessive hair loss and dandruff.

Diseases and paste
The medicinal plants have to be grown without chemical fertilizers and use of pesticides. Organic manures like, Farm Yard Manure (FYM),
Vermi-Compost, Green Manure etc. may be used as per requirement of the species. To prevent diseases, bio-pesticides could be prepared (either single or mixture) from Neem (kernel, seeds & leaves),
Chitrakmool, Dhatura, Cow's urine etc.
Liquorice Juice or Extract
The manufacture of Liquorice Juice, or Extract the roots and runners of both wild and cultivated plants are taken up
and crushed under millstones to a pulp. Then it is transferred to boilers and boiled in water over a naked fire, the decoctions are run off and then evaporated in copper vessels over direct heat, till a suitable consistency is
obtained. It is being constantly stirred to prevent burning. While warm, the mass is taken out and rolled into sticks, stamped and stacked on boards to dry.
Extract of Liquorice in rolls has a black colour, is somewhat glossy and has a sharp and shining fracture.
Storage and Trading
The dry roots should possess not more than 10% moisture when these are ready to be stored in polythene lined bags. The roots are cut into pieces of convenient size and shorted into grades, based on thickness.
The yield of dry root at Hissar
(Haryana) is recorded between 70 to 80 q/ha. At Anand 10 to 20 months crop has given an average yield of 20 to 25 q/ha.
Modern Study Modern research has shown it to have effects upon, amongst other organs, the endocrine system and liver. The triterpenes of Glycyrrhiza are metabolized in the body to molecules that have a similar structure to the adrenal cortex hormones. This is possibly the basis of the herbs anti-inflammatory action.
Economy
Return Rs. 3,50,000/- to 4,00,000/-per hectare (YEAR-2001).
Due to the volatile market for medicinal plants the economics may vary.
Toxicity
Excessive consumption of liquorice or
liquorices candy is known to be toxic to
the liver and cardiovascular system, and may produce hypertension and
edema.
There is a small possibility of effecting electrolyte balance with extended use of large doses of licorice. It has an ACTH like effect causing retention of sodium thus raising BP.
It is best to avoid Licorice if the patient has hypertension, kidney disease or during pregnancy.
It may interfere with the calcium and potassium absorption. Do not use if you are suffering from osteoporosis, hypertension.
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